Which of the following is a contraindication to nitroglycerin administration?

• A. Hypotension (SBP < 100 mmHg)
• B. Erectile dysfunction meds within 48 hours
• C. Hypersensitivity
• D. Pediatric not permitted

Answer: (A)

Nitroglycerin is given to reduce cardiac workload by dilating veins and lowering preload, but it can drop blood pressure further if the patient is already hypotensive. An SBP below 100 mmHg means administering nitroglycerin could cause dangerous systemic hypotension and inadequate perfusion, so it is considered a contraindication.

Other common contraindications include taking erectile dysfunction medications within the last 24–48 hours, which can cause severe hypotension when combined with nitrates, and hypersensitivity to nitrates. The statement about pediatric use isn’t typically used to decide nitroglycerin in adults, as it points to lack of indication rather than an immediate safety contraindication in adult patients.