Which adverse reaction is associated with Diazepam in this protocol?

• A. Tachycardia
• B. Hypertension
• C. Respiratory depression
• D. Nausea only

Answer: (C)

Diazepam is a benzodiazepine that enhances GABAergic inhibition in the brain, producing sedation and CNS depression. The notable adverse reaction to monitor in this protocol is respiratory depression, because deeper CNS depression can blunt the respiratory drive, especially at higher doses or when combined with other depressants like opioids or alcohol. That’s the most clinically important risk here. Tachycardia and hypertension aren’t typical direct effects of diazepam, and while nausea can occur, it doesn’t carry the same immediate threat to breathing as respiratory depression.