What is the recommended adult dose for Epinephrine 1:100,000 in this protocol?

• A. 0.1 mcg/kg IV
• B. 100 mcg IV
• C. 10 mcg IV/IO
• D. 1 mg IV

Answer: (C)

In this protocol, the adult IV/IO dose of epinephrine at a 1:100,000 dilution is a fixed bolus of 10 micrograms. Since 1:100,000 epinephrine contains 10 mcg per milliliter, this dose is delivered as 1 mL of the solution. This small bolus provides vasopressor effect to improve blood pressure and perfusion during shock or resuscitation while minimizing risks seen with higher doses.

It helps to contrast with other dilutions: a 1:10,000 preparation carries a much higher concentration, making a 1 mg dose feasible only as a cardiac-arrest dose with a large volume, and a 1:1,000 dilution is used for other clinical scenarios like anaphylaxis. The protocol specifies the 1:100,000 bolus because it achieves the needed pressor effect without the excessive adrenergic load of the higher-concentration preparations.