What is the primary action of Solu-CorteF?

• A. Anti-inflammatory, replaces absent glucocorticoids, suppresses immune response
• B. Analgesic
• C. Diuretic
• D. Vasodilator

Answer: (A)

Solu-Cortef is a glucocorticoid. Its primary action is anti-inflammatory and immunosuppressive, achieved by binding glucocorticoid receptors and altering gene expression to reduce inflammatory mediators such as cytokines and prostaglandins, as well as stabilizing lysosomes and decreasing capillary permeability. It also provides hormone replacement in adrenal insufficiency, which helps suppress an overactive immune response when cortisol is deficient. Because of these actions, it’s not simply an analgesic, diuretic, or vasodilator—the effects described by those options don’t reflect how a glucocorticoid works.