What is the antidote/reversal agent for calcium channel blocker overdose with bradycardia and hypotension?

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Multiple Choice

What is the antidote/reversal agent for calcium channel blocker overdose with bradycardia and hypotension?

Explanation:
Calcium channel blocker overdose with bradycardia and hypotension is treated by giving calcium to counteract the blockade and restore calcium-dependent cardiac and vascular function. Calcium chloride provides immediate calcium that helps overcome the block at the L-type calcium channels, improving heart rate, contractility, and vascular tone. The recommended approach is a slow IV/IO bolus of 1 g of a 10% calcium chloride solution, with careful monitoring; repeat dosing or an infusion may be used based on response. Be mindful of potential vein irritation and the risk of hypercalcemia, so use good IV access and monitor closely. Other options may support perfusion transiently but do not reverse the pharmacologic blockade like calcium does.

Calcium channel blocker overdose with bradycardia and hypotension is treated by giving calcium to counteract the blockade and restore calcium-dependent cardiac and vascular function. Calcium chloride provides immediate calcium that helps overcome the block at the L-type calcium channels, improving heart rate, contractility, and vascular tone. The recommended approach is a slow IV/IO bolus of 1 g of a 10% calcium chloride solution, with careful monitoring; repeat dosing or an infusion may be used based on response. Be mindful of potential vein irritation and the risk of hypercalcemia, so use good IV access and monitor closely. Other options may support perfusion transiently but do not reverse the pharmacologic blockade like calcium does.

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